Recent studies have demonstrated significant cross talk

2025-04-17

Recent studies have demonstrated significant cross-talk between XRCC1 (a key player in Y-27632 dihydrochloride excision repair (BER) and single strand break repair) and DDR [30], [31], [32]. ATM and DNA-PKcs are known to be involved in the phosphorylation of XRCC1 to promote BER [30], [31]. We have

In Rainey et al published the results of a

2025-04-17

In 2008, Rainey et al. published the results of a targeted compound library screen for potential inhibitors of the ATM kinase. In this study, the compound CP466722 was identified as a highly selective and rapidly reversible ATM inhibitor, which did not inhibit PI3K or related PIKK family members. Mo

Thieno-GTP

2025-04-16

N1-Propyl-Pseudo-UTP

2025-04-16

Desthiobiotin-16-UTP

2025-04-16

HotStart™ 2X Green qPCR Master Mix

2025-04-16

D-Lin-MC3-DMA

2025-04-15

Cell Counting Kit-8 (CCK-8)

2025-04-15

Concanavalin A (Con A)-HyperFluor™ 488

2025-04-15

Cy5-UTP

2025-04-15

Sulfo-NHS-Biotin A different mechanism has been suggested fo

2025-04-15

A different mechanism has been suggested for the role of TRX1 in ASK1 regulation based on disulfide bond-mediated ASK1 multimerization and its reduction through the thiol-reductase activity of TRX1 (Nadeau et al., 2007, Nadeau et al., 2009). In this model, oxidative stress induces intermolecular dis

HyperScribe™ T7 High Yield RNA Synthesis Kit

2025-04-14

2025-04-14

Phosphatase Inhibitor Cocktail 2 (100X in ddH2O)

2025-04-14

There is little question that as we become more proficient

2025-04-12

There is little question that as we become more proficient in the diagnosis of arginase 1 deficiency individuals with intermediary elevations in arginine on newborn screening and partial defects in enzymatic activity will be found. There are no reliable data to determine a safe level of arginine and