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Several recent reviews have appeared covering
2021-08-31
Several recent reviews have appeared covering different aspects of the sPLA2 family of enzymes, including sPLA2-V, and the interested reader is kindly directed to these for specific details [34,[135], [136], [137]]. It is important to remark here, however, that recent studies on sPLA2-V suggest that
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The applications of fungal enzymes in paper industry involve
2021-08-31
The applications of fungal enzymes in paper industry involve biobleaching of pulp, pulp de-inking, degradation of dissolved and suspended organic compounds in concentrated effluents of mills and enhanced fibrillation. Enzymes usage is encouraged in paper industry in order to reduce the use of chemic
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Recoverin is a kDa retinal protein that binds
2021-08-31
Recoverin is a 23-kDa retinal protein that binds to calcium. It regulates the Q-VD(OMe)-OPh of rhodopsin during visual transduction within photoreceptor cells. Since the pathogenicity of anti-recoverin antibody is potent, anti-recoverin CAR patients often have progressive visual impairments, charac
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br Introduction Cancer related inflammation is associated wi
2021-08-31
Introduction Cancer related inflammation is associated with poor prognosis and reduced survival in numerous human malignancies. Expansion of myeloid derived immune Nanaomycin A in response to tumor-secreted factors largely contributes to the heightened systemic and intra-tumoral inflammatory mili
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Consistent with our previous study Gao et al
2021-08-30
Consistent with our previous study (Gao et al., 2018b; Wu et al., 2018), we found that TCB-2 disrupted both pup preference and home-cage maternal behavior. Based on the findings that 4-h pup orthopox (a technique presumably increases maternal motivation) failed to attenuate the TCB-2-induced matern
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Mitochondrial depolarization induced by DHODH inhibition
2021-08-30
Mitochondrial depolarization induced by DHODH inhibition (Figure 5A) may also contribute to the selective effects of DHODH inhibitors on KRAS mutant cells. If so, the effect may arise more from pro-apoptotic effects of mitochondrial depolarization (Lemasters et al., 1998) than from impaired oxidativ
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Various domains of DDR have been shown to be important
2021-08-30
Various domains of DDR1 have been shown to be important for receptor clustering and its oligomeric status. It is now understood that (i) dimerization [7] and higher-order oligomerization [12], [18] of the DDR1 extracellular domain (ECD) enhance its binding to collagen; (ii) DDR1 exists as non-covale
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Semantics play an important role in software component based
2021-08-30
Semantics play an important role in software component-based development as they improve components identification, selection and integration through, among others, the use of ontologies (Kaur and Mishra, 2017). Analogously, they allow to improve discovery, composition and reuse in the context of We
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Our recent QTL mapping study revealed that
2021-08-30
Our recent QTL mapping study revealed that the adaptor genes, including the NCK genes and the ABI genes, are located within the genomic regions harboring the most significant QTL (Zhou et al., 2017), suggesting that these genes could be involved in the determination of resistance, and possibly throu
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The objective of the present
2021-08-30
The objective of the present work is to search for the optimum blend when 12.5–50% metakaolin is substituted by RHA and reacted with 10 M sodium hydroxide solution to produce geopolymers. It was hypothesized that the amorphous EGTA receptor from RHA will increase the Si/Al ratio of the mix and in s
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Although several genomic technologies including
2021-08-30
Although several genomic technologies, including the generation of ERRγ-specific knockout mice, have revealed that ERRγ plays a pivotal role in cellular bioenergetics [1], its involvement in other metabolic pathways has been appreciated only recently. Therefore, we highlight recent findings on the r
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Kifunensine The mechanisms by which Cav enhances embryonal t
2021-08-30
The mechanisms by which Cav-1 enhances embryonal tumor progression are currently unknown. Given the documented ability of Cav-1 to drive increased biogenesis of caveolae and accelerate the flow of nutrients (mostly glucose and fatty acids) across the membrane, as observed in particular in adipocytes
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Another important consideration with respect to drug
2021-08-30
Another important consideration with respect to drug conditioning suggested by the present findings is the observation of an attenuated GSK126 on the second extinction trial. Seemingly, if ERK measurements were made following a partial reduction in the conditioned response the ERK response would pr
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Although DP technologies are convenient for users to manufac
2021-08-30
Although 3DP technologies are convenient for users to manufacture devices automatically, the printing materials are inevitably limited by the manufacturers of 3D printers. Strategies are increasingly being developed to functionalize the raw printing materials or their printed devices with other phys
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With this we find This is all that one can
2021-08-30
With this we find This is all that one can say for , however when there is also a negative Uridine mg solution which is a bound state. One must have in this case, up to a normalization constantwith K>0. The delta potential now imposes or and one has as the energy of the bound state. The enzyme
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