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br Conclusions br Declaration of interest br Acknowledgement
2020-07-31
Conclusions Declaration of interest Acknowledgements Introduction Uncorrected obesity has been a major health problem and the prevalence of obesity is fast rising reaching an epidemic proportion [[1], [2], [3]]. Ample of clinical and experimental evidence has suggested that obesity leads
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Although Bach is expressed in diverse cell
2020-07-31
Although Bach1 is expressed in diverse cell types, no clear defects are observed in Bach1-deficient mice under normal conditions [10]. Bach1-deficient mice also exhibit elevated disease tolerance in various models, including atherosclerosis in ApoE double-knockout mice [38], lung damage after high o
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br Material methods br Results br Discussion In the present
2020-07-31
Material & methods Results Discussion In the present study, male zebrafish of the AB line were classified as bold and shy, respectively, based on activity and risk-taking behavior in the novel tank diving test, and extreme bold and shy individuals were selected for analysis of whole Puromyc
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br Results br Discussion TLS is
2020-07-31
Results Discussion TLS is an essential biological process that allows both prokaryotic and eukaryotic 234 2 to cope with unrepaired DNA lesions. While it is clear that TLS is important for maintaining cell viability, the molecular mechanisms accounting for how certain DNA polymerases efficient
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Taking a pragmatic approach with
2020-07-31
Taking a pragmatic approach with a view to complete the study and because chemotherapy regimens in NETs are not standardized, we do not impose a specific regimen in both arms. However, one regimen in each arm is recommended in order to reduce heterogeneity: the ALKY-based chemotherapy arm will recei
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br Material and methods br Results br Discussion Increasing
2020-07-31
Material and methods Results Discussion Increasing effort is now focused on engineering oilseeds to provide renewable, cost-competitive and environmentally friendly sources of industrial oils as alternatives to those currently derived mainly from non-renewable petroleum sources. To meet thi
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br Conflicts of interest br Acknowledgments
2020-07-31
Conflicts of interest Acknowledgments This study was supported by the Beijing Natural Science Foundation (No.7192015), the Great Wall scholars program of Beijing Municipal Education Commission (No.CIT&TCD20180308) and Beijing Municipal Commission of Education Research Projects (Grant No. KM201
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N Alkylated quinolinium dyes are
2020-07-30
N-Alkylated quinolinium dyes are the common fluorescence molecules used in fluorescence sensing and cell imaging because of their attractive optical properties as well as high DNA binding affinities.13, 14, 15, 16, 17, 18, 19, 20 Moreover, the quinolinium moiety usually plays the role of donor in va
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Within this context we are interested in evaluating
2020-07-30
Within this context, we are interested in evaluating DHODH as a potential target for the development of anti-schistosomiasis drugs. Schistosomiasis is a chronic parasitic disease caused by different species of blood fluke parasites of the genus Schistosoma. This disease is the deadliest among the ne
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In this study EDC NHS crosslinked collagen films
2020-07-30
In this study, EDC/NHS crosslinked collagen films were derivatised with VWFIIINle-containing THPs and the effect on VWF and DDR2 activity was examined. First, we investigated restoration of the binding of DDR2 and VWF A3. Cell behavior beyond simple binding was also investigated through DDR2 trk rec
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mitotic inhibitors Synthetic cytokine biology has become an
2020-07-30
Synthetic cytokine biology has become an important research area with novel solutions and ideas for therapeutic approaches, for example, synthekines, fusokines, immunocytokines, neoleukins, MESA receptors, or synthetic Notch or cytokine receptors. In addition to their huge impact on health and disea
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br Development and germination of cereal
2020-07-30
Development and germination of cereal seeds Caryopses (cereal grains) are the propagation units of many monocot species, such as wheat, triticale, barley and other cereal species. A caryopsis is a type of dry fruit composed of three tissues: the diploid embryo, the triploid endosperm and the mate
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Cell lines which possess microglial or neuronal properties a
2020-07-30
Cell lines which possess microglial or neuronal properties are uncomplicated and convenient in vitro models for studying thiostrepton injury at the cellular and molecular levels. Microglial BV-2 cells are derived from the immortalized mouse microglia and exhibit many of the morphological, phenotypi
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IPT b s low expression
2020-07-30
IPT5b\'s low expression level in dwarfing rootstocks suggests its key role in regulating cytokinin biosynthesis (Fig. 1b). The known IPT proteins that are highly homologous to apple IPT5b were found in plants by homologous alignment (Fig. 2a), and further analysis indicated a common structural chara
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br Results and discussion br Conclusions A total of
2020-07-30
Results and discussion Conclusions A total of 3 ambient variables and 6 flow- and temperature-related operating variables were considered to develop Cox regression models for the four transitional statuses and their degree of significance was examined by their hazard ratios. The temperature of
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